Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL11054146 | 0.91 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TSHRHTTPPARG | |
| SCHEMBL11052452 | 0.88 | MAOB (0.45) | CYP3A4ALDH1A1MAOBHTTPPARG | |
| Butadiene SCHEMBL11055970 | 0.87 | HTT (0.40) | CYP3A4ALDH1A1HTTPPARGNFE2L2 | |
| SCHEMBL9767734 | 0.87 | HTT (0.42) | CYP3A4ALDH1A1HTTPPARGNFE2L2 | |
| SCHEMBL20474516 | 0.85 | HTT (0.43) | CYP3A4ALDH1A1HTTPPARGNFE2L2 | |
| SCHEMBL10777428 | 0.85 | HTT (0.43) | CYP3A4ALDH1A1HTTPPARGNFE2L2 | |
| SCHEMBL11174960 | 0.82 | CYP3A4 (0.53) | CYP3A4ALDH1A1TSHRMAOBLMNA | |
| Styrene SCHEMBL1979409 | 0.82 | TSHR (0.52) | ALDH1A1TSHRHTTPPARGNFE2L2 | |
| Styrene SCHEMBL8173415 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTPPARGNFE2L2 | |
| Styrene SCHEMBL5175176 | 0.81 | CYP3A4 (0.51) | CYP3A4ALDH1A1TSHRMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425462-A | SODIUM STYRENE SULFONATE COPOLYMER | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-01-10 | — | — | US | disclosed |