SCHEMBL11057726

SCHEMBL11057726

CCCCCCCCCCCCOC(=O)CS(=O)(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.53
HSD11B1 P28845 3/20 0.51
TP53 P04637 2/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
KMT2A Q03164 1/20 0.50
NAAA Q02083 1/20 0.49
GAA P10253 1/20 0.48
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
HSD17B10 Q99714 1/20 0.47
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PPARG P37231 3/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PSIP1 O75475 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14456209 1.00 TSHR (0.53) TSHRALDH1A1LMNAHSD11B1TP53
SCHEMBL5093364 1.00 TSHR (0.53) TSHRALDH1A1LMNAHSD11B1TP53
SCHEMBL28727247 0.94 HSD11B1 (0.54) TSHRALDH1A1HSD11B1TP53CYP3A4
SCHEMBL14456210 0.87 KMT2A (0.56) TSHRALDH1A1LMNAHSD11B1CYP3A4
SCHEMBL28727264 0.86 KMT2A (0.51) TSHRALDH1A1LMNAHSD11B1KMT2A
SCHEMBL29249185 0.85 MMP9 (0.50) ALDH1A1HSD11B1KMT2ANPSR1
SCHEMBL25061975 0.84 MAPK1 (0.49) ALDH1A1HSD11B1TP53MAPK1KMT2A
SCHEMBL2024141 0.81 KMT2A (0.73) ALDH1A1HSD11B1TP53MAPK1KMT2A
SCHEMBL28303800 0.80 TSHR (0.45) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL6751981 0.80 KMT2A (0.71) ALDH1A1HSD11B1TP53MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4455368-A Silver halide photographic light-sensitive material containing a UV absorbing polymer latex FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed