Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | WRN | Q14191 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874765 | 0.82 | ALDH1A1 (0.55) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL24978575 | 0.80 | MGLL (0.50) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL2756782 | 0.78 | ALDH1A1 (0.64) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL10759118 | 0.78 | ALDH1A1 (0.63) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL24687996 | 0.76 | CYP3A4 (0.56) | ALDH1A1HPGDCYP1A2CYP2C19RAB9A | |
| SCHEMBL10609594 | 0.76 | ALDH1A1 (0.61) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL1271868 | 0.75 | ALDH1A1 (1.00) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL11213409 | 0.74 | ALDH1A1 (0.59) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL29048036 | 0.74 | ALDH1A1 (0.59) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL9914133 | 0.73 | ALDH1A1 (0.58) | ALDH1A1BLMHPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448906-A | N-HYDROXYMETHY- OR N-CARBOXY METHYLAMALEIDE FOR USE IN PAINTS AS BIOCIDE | NUODEX INC. (US) | 1984-05-15 | — | — | US | disclosed |