Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040110 | 0.80 | USP5 (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11038236 | 0.79 | BCHE (0.39) | ALDH1A1KDM4EBCHEMAPTMAPK1 | |
| SCHEMBL11038204 | 0.78 | TLR7 (0.41) | ALDH1A1SMN1; SMN2KDM4ETSHRBCHE | |
| SCHEMBL11040963 | 0.78 | USP5 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11248849 | 0.77 | BCHE (0.38) | ERN1BCHE | |
| SCHEMBL11038226 | 0.77 | TLR7 (0.42) | ALDH1A1SMN1; SMN2KDM4ETSHRBCHE | |
| SCHEMBL11252296 | 0.76 | BCHE (0.39) | KDM4ERAB9ABCHENPC1 | |
| SCHEMBL11053054 | 0.76 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL11052293 | 0.75 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11257731 | 0.72 | TLR7 (0.38) | ALDH1A1SMN1; SMN2KDM4ETSHRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038528-B1 | DIHYDRO-AS-TRIAZINO(5,6-C)QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1984-08-08 | — | — | EP | disclosed |
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | disclosed |