Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11052293 | 0.99 | ALDH1A1 (0.34) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11038147 | 0.81 | USP5 (0.35) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11037314 | 0.80 | USP5 (0.34) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11038211 | 0.80 | PDE4A (0.41) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11036595 | 0.79 | USP5 (0.34) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11038010 | 0.79 | TLR7 (0.42) | TSHRSMN1; SMN2PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL11036638 | 0.79 | PDE4A (0.40) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11037970 | 0.79 | LMNA (0.33) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11249911 | 0.78 | BCHE (0.37) | KMT2ABCHE | |
| SCHEMBL11040120 | 0.78 | DUSP10 (0.33) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038528-B1 | DIHYDRO-AS-TRIAZINO(5,6-C)QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1984-08-08 | — | — | EP | disclosed |
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | disclosed |