Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620729 | 0.94 | SHBG (0.53) | CYP4F2CYP4A11SHBGFAAHESR1 | |
| Acefluranol SCHEMBL2110861 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11SHBGFAAHESR1 | |
| SCHEMBL17356430 | 0.81 | MRGPRX4 (0.47) | CYP4F2CYP4A11FAAHHIF1APTGS2 | |
| SCHEMBL14268223 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11FAAHPTGS1MRGPRX4 | |
| Bifluranol SCHEMBL23620730 | 0.78 | SHBG (0.65) | SHBGESR1HIF1APTGS2PTGS1 | |
| SCHEMBL26239373 | 0.76 | PTGS2 (0.40) | CYP4F2CYP4A11FAAHHIF1APTGS2 | |
| SCHEMBL178987 | 0.75 | TSHR (0.55) | HIF1APTGS1KDM4EALDH1A1GAA | |
| Bifluranol SCHEMBL131387 | 0.74 | SHBG (0.73) | SHBGESR1HIF1APTGS2PTGS1 | |
| Bifluranol SCHEMBL29928815 | 0.74 | SHBG (0.73) | SHBGESR1HIF1APTGS2PTGS1 | |
| Bifluranol SCHEMBL1650515 | 0.74 | SHBG (0.73) | SHBGESR1HIF1APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427697-A | ANTIESTROGENS | BIOREX LABORATORIES LIMITED (GB) | 1984-01-24 | — | — | US | disclosed |