SCHEMBL11058348

SCHEMBL11058348

NC(=O)CCc1ccc(O)cc1O

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28057532 0.85 CHRNA7 (0.62) TYR
SCHEMBL8100867 0.84 TYR (0.68) TYR
SCHEMBL7699472 0.83 TYR (0.41) TYR
SCHEMBL490491 0.82 POLB (0.67) TYR
SCHEMBL29998634 0.82 POLB (0.67) TYR
SCHEMBL28179666 0.81 HSD17B10 (0.42) TYR
SCHEMBL23276485 0.81 TYR (0.63) TYR
SCHEMBL26046393 0.81 TYR (0.63) TYR
SCHEMBL28875498 0.80 MEN1 (0.58) TYR
SCHEMBL7794268 0.79 EGFR (0.49) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4448730-A ANTITUMOR AGENTS RIET BARTHOLOMEUS VAN T 1984-05-15 US disclosed