SCHEMBL7699472

SCHEMBL7699472

NC(=O)CCc1ccc(O)cc1I

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.41
CHRNA7 P36544 1/20 0.41
MPO P05164 1/20 0.39
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058348 0.83 TYR (0.63) TYR
SCHEMBL3652088 0.83 POLB (0.51) TYRCHRNA7
SCHEMBL28179666 0.80 HSD17B10 (0.42) TYRCHRNA7
SCHEMBL28057532 0.80 CHRNA7 (0.62) TYRCHRNA7MPO
SCHEMBL1726385 0.76 NR1I2 (0.46) TYR
SCHEMBL423696 0.75 TYR (0.56) TYR
SCHEMBL7794268 0.74 EGFR (0.49) TYRCHRNA7MPO
SCHEMBL26586622 0.72 TYR (0.46) TYR
SCHEMBL20153030 0.72 CHRNA7 (0.38) TYRCHRNA7
SCHEMBL3410041 0.71 PTGDR2 (0.37) MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1224354-A1 WRINKLE RESISTANT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2002-07-24 EP disclosed
WO-2001031113-A1 WRINKLE RESISTANT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2001-05-03 WO disclosed
EP-1019447-A1 ETHOXYLATED AMINO-FUNCTIONAL POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-07-19 EP disclosed
WO-1999016811-A1 ETHOXYLATED AMINO-FUNCTIONAL POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1999-04-08 WO disclosed