Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058348 | 0.85 | TYR (0.63) | TYR | |
| SCHEMBL437626 | 0.84 | CHRNA7 (0.64) | CHRNA7FFAR1FFAR4POLB | |
| SCHEMBL9160970 | 0.84 | MPO (0.56) | CHRNA7MPOFFAR1FFAR4 | |
| SCHEMBL1404941 | 0.82 | CHRNA7 (0.62) | CHRNA7TYRFFAR1FFAR4POLB | |
| SCHEMBL29837313 | 0.81 | CHRNA7 (0.49) | CHRNA7TYR | |
| SCHEMBL24632659 | 0.81 | FFAR1 (0.49) | CHRNA7MPOFFAR1FFAR4 | |
| SCHEMBL26938435 | 0.81 | PDPK1 (0.56) | CHRNA7MPOFFAR1FFAR4 | |
| SCHEMBL7699472 | 0.80 | TYR (0.41) | CHRNA7MPOTYR | |
| SCHEMBL3972328 | 0.79 | TAAR1 (0.54) | CHRNA7TYR | |
| SCHEMBL28179666 | 0.79 | HSD17B10 (0.42) | CHRNA7TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103200820-B | As the substd quinolines compound of GSNO reductase inhibitor | Nivalis Therapeutics (US) | 2016-04-06 | — | — | CN | disclosed |