SCHEMBL11058375

SCHEMBL11058375

C=CC=CC(=C)Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.40
CES2 O00748 1/20 0.40
AKR1B1 P15121 1/20 0.40
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CTBP2 P56545 1/20 0.33
EPHX2 P34913 1/20 0.33
MAOB P27338 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22590584 0.81 CES1 (0.38) CES1CES2AKR1B1MEN1KMT2A
Benzene SCHEMBL28149238 0.79 CES1 (0.46) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL1073587 0.79 CES1 (0.46) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL4933301 0.78 CES1 (0.48) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL22432863 0.77 CES1 (0.38) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL21169581 0.77 CES1 (0.38) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL3485127 0.77 CES1 (0.50) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL24971737 0.76 LMNA (0.36) MEN1KMT2ATSHRALDH1A1
SCHEMBL31092997 0.74 HDAC3 (0.40) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL31092961 0.74 MEN1 (0.48) MEN1KMT2AHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4485218-A VINYLTOLUENE, TRIMETLOLPROPANE TRIMETHACRYLATE, PEROXIDE CURING AGENT, INHIBITOR GENERAL ELECTRIC COMPANY (US) 1984-11-27 US claimed