Benzene

Benzene

SCHEMBL28149238

C=CC(=C)Cc1ccccc1.c1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.46
CES2 O00748 1/20 0.46
AKR1B1 P15121 1/20 0.46
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
MAOB P27338 1/20 0.39
AKT1 P31749 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CTBP2 P56545 1/20 0.38
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1073587 1.00 CES1 (0.46) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL31707502 0.84 GRIN2D (0.36) ALDH1A1MEN1KMT2ACYP3A4
SCHEMBL13017152 0.79 CES1 (0.44) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL3485127 0.79 CES1 (0.50) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL11058375 0.79 CES1 (0.40) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL8550603 0.78 CES1 (0.48) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL12802353 0.77 CTBP2 (0.40) ALDH1A1MEN1KMT2AL3MBTL1CTBP2
SCHEMBL610421 0.77 LOXL2 (0.39) ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL12802223 0.77 LPL (0.40) ALDH1A1CYP2C9
SCHEMBL3701685 0.77 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108681217-A Toner 佳能株式会社 2018-10-19 CN disclosed
CN-104106008-B Magnetic color tuner 佳能株式会社 2017-06-23 CN disclosed
CN-104024950-B Magnetic toner 佳能株式会社 2017-05-24 CN disclosed