Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061057 | 0.94 | MAP3K7 (0.37) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11063674 | 0.93 | CYP3A4 (0.38) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11062429 | 0.78 | MAPT (0.38) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11062623 | 0.77 | LMNA (0.37) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11060720 | 0.71 | CYP3A4 (0.36) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL3428654 | 0.71 | TP53 (0.53) | LMNAMAPTTSHRTP53HSD17B10 | |
| SCHEMBL11058678 | 0.68 | LMNA (0.39) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL8937059 | 0.66 | CDK1 (0.49) | LMNACYP3A4MAPTMEN1NR1I2 | |
| 6-(Decyloxy)Purine SCHEMBL6234481 | 0.66 | CDK1 (0.49) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL5175458 | 0.66 | CDK1 (0.49) | LMNACYP3A4MAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |