Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13557182 | 0.63 | MMP2 (0.67) | ALDH1A1MMP2CA1HPGDMEN1 | |
| SCHEMBL10795112 | 0.61 | MEN1 (0.56) | ALDH1A1NLRP3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL411437 | 0.61 | MMP2 (0.49) | ALDH1A1NLRP3MMP2SMN1; SMN2FOLH1 | |
| SCHEMBL11607679 | 0.61 | BCHE (1.00) | ALDH1A1NLRP3BCHEACHEMAPT | |
| SCHEMBL257997 | 0.59 | MAPT (0.64) | ALDH1A1BCHEACHETP53MAPT | |
| SCHEMBL11973569 | 0.58 | MMP2 (0.59) | ALDH1A1MMP2SMN1; SMN2ACHECA1 | |
| SCHEMBL6981947 | 0.58 | MMP2 (0.59) | ALDH1A1MMP2SMN1; SMN2ACHECA1 | |
| SCHEMBL3380070 | 0.58 | MAOA (0.58) | ALDH1A1NLRP3SMN1; SMN2BCHEACHE | |
| SCHEMBL3832921 | 0.58 | NPSR1 (0.55) | ALDH1A1SMN1; SMN2CA1MAPTPKM | |
| SCHEMBL3832918 | 0.58 | NPSR1 (0.55) | ALDH1A1SMN1; SMN2CA1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440683-A | Cyclization to form cephem ring and azetidinone intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| US-4346218-A | DECYCLIZATION OF AN AZETIDINOTHIAZOLINE | SHIONOGI & CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |
| US-4332722-A | BICYCLIC AZETIDINOTHIAZOLINES | SHIONOGI & CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4160085-A | Cyclization to form cephem ring and intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4079181-A | INTERMEDIATES FOR 3-HYDROXY-3-CEPHEM COMPOUNDS | SHIONOGI & CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |