Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421914 | 0.87 | CYP19A1 (0.60) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL1984504 | 0.86 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL4238772 | 0.86 | MAPT (0.62) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL30365378 | 0.86 | MAPT (0.62) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL9416505 | 0.84 | CYP19A1 (0.61) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL7573078 | 0.83 | CYP19A1 (0.63) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL11796767 | 0.83 | TDP1 (0.65) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL10454986 | 0.83 | MAPT (0.56) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL13159002 | 0.83 | GPR35 (0.53) | MAPTALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL2084753 | 0.83 | HTT (0.67) | MAPTALDH1A1LMNAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | claimed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | disclosed |