Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058808 | 1.00 | ALDH1A1 (0.31) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL11053538 | 1.00 | ALDH1A1 (0.31) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL19766904 | 0.80 | AKR1C4 (0.35) | — | |
| SCHEMBL6909060 | 0.79 | GLB1 (0.33) | — | |
| SCHEMBL12237117 | 0.78 | CA1 (0.34) | — | |
| SCHEMBL18853799 | 0.72 | AKR1C4 (0.52) | ALDH1A1 | |
| SCHEMBL18853787 | 0.72 | AKR1C4 (0.52) | ALDH1A1 | |
| SCHEMBL6727788 | 0.72 | AKR1C4 (0.52) | ALDH1A1 | |
| SCHEMBL669993 | 0.72 | AKR1C4 (0.52) | ALDH1A1 | |
| SCHEMBL29517213 | 0.72 | AKR1C4 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455421-A | ANTIFERTILITY, ANTIULCER AGENTS; TETRAZOLE DERIVATIVES | PFIZER INC. (US) | 1984-06-19 | — | — | US | disclosed |
| US-4365077-A | ANTIFERTILITY, ANTIULCER | PFIZER INC. (US) | 1982-12-21 | — | — | US | disclosed |
| US-4157341-A | 11-Desoxy-16-aryloxy-ω-tetranorprostaglandins | PFIZER INC. (US) | 1979-06-05 | — | — | US | disclosed |
| US-3984400-A | 11-Desoxy-16-aryl-ω-tetranorprostaglandins | PFIZER INC. (US) | 1976-10-05 | — | — | US | disclosed |