Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180824 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL6727796 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL669994 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL18853787 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL18853799 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL29517213 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL6727788 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL18853784 | 0.85 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2TBXA2RSLC6A12 | |
| SCHEMBL22814915 | 0.84 | AKR1C4 (0.43) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL22814859 | 0.84 | AKR1C4 (0.36) | AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223680-B1 | Combination of monosaccharides and exfoliating agents and its cosmetic use | L'ORÉAL (FR) | 2017-10-18 | — | — | EP | claimed |
| EP-2448549-B1 | COSMETIC USE OF A JASMONIC ACID DERIVATIVE FOR TREATING THE HAIR AND THE SCALP | L'ORÉAL (FR) | 2017-10-11 | — | — | EP | claimed |
| EP-1333021-B1 | COMPOSITIONS CONTAINING DERIVATIVES OF JASMONIC ACID AND THEIR USE FOR STIMULATING SKIN PEELING | L'ORÉAL (FR) | 2017-10-04 | — | — | EP | claimed |
| EP-3168206-A1 | COMPOSITIONS COMPRISING DERIVATIVES OF JASMONIC ACID, AND USE OF SAID DERIVATIVES TO PROMOTE EXFOLIATION | L'OREAL (FR) | 2017-05-17 | — | — | EP | claimed |
| US-8679513-B2 | Cosmetic use of a jasmonic acid derivative for treating the hair and the scalp | L'OREAL (FR) | 2014-03-25 | — | — | US | claimed |
| US-20120157527-A1 | COSMETIC USE OF A JASMONIC ACID DERIVATIVE FOR TREATING THE HAIR AND THE SCALP | L'OREAL (FR) | 2012-06-21 | — | — | US | claimed |
| EP-2448549-A2 | COSMETIC USE OF A JASMONIC ACID DERIVATIVE FOR TREATING THE HAIR AND THE SCALP | L'Oréal (FR) | 2012-05-09 | — | — | EP | claimed |
| US-20110152150-A1 | CLEANSING COMPOSITION | L'OREAL (FR) | 2011-06-23 | — | — | US | claimed |
| WO-2011000903-A2 | COSMETIC USE OF A JASMONIC ACID DERIVATIVE FOR TREATING THE HAIR AND THE SCALP | L'OREAL (FR) | 2011-01-06 | — | — | WO | claimed |
| EP-2223680-A2 | Combination of monosaccharides and exfoliating agents and its cosmetic use | L'Oréal (FR) | 2010-09-01 | — | — | EP | claimed |
| US-20100179222-A1 | COMPOSITIONS COMPRISING JASMONIC ACID DERIVATIVES AND USE OF THESE DERIVATIVES | L'OREAL S.A. | 2010-07-15 | — | — | US | claimed |
| US-20100168041-A1 | COMBINATION OF MONOSACCHARIDES AND DESQUAMATING AGENTS, AND USE THEREOF | L'OREAL (FR) | 2010-07-01 | — | — | US | claimed |
| US-20040029839-A1 | Compositions comprising jasmonic acid derivatives and use of these derivatives | L'OREAL S.A. (FR) | 2004-02-12 | — | — | US | claimed |
| EP-1333021-A2 | Compositions containing derivatives of jasmonic acid and their use for stimulating skin peeling | L'OREAL (FR) | 2003-08-06 | — | — | EP | claimed |
| US-12256733-B2 | Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an acid or silver-based compound, and cosmetic composition containing same | L'OREAL (FR) | 2025-03-25 | — | — | US | disclosed |
| US-12226509-B2 | Cosmetic composition comprising a pasty fatty substance and a non-ionic derivative of hydrophobic-modified cellulose | L'OREAL (FR) | 2025-02-18 | — | — | US | disclosed |
| US-20230065230-A1 | ANTIMICROBIAL MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL)BUTAN-2-ONE AND AN ACID OR SILVER-BASED COMPOUND, AND COSMETIC COMPOSITION CONTAINING SAME | L'OREAL (FR) | 2023-03-02 | — | — | US | disclosed |
| US-7250160-B2 | Jasmonic acid and jasmonic acid ester stereoisomers and compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-07-31 | — | — | US | disclosed |
| US-20040029839-A1 | Compositions comprising jasmonic acid derivatives and use of these derivatives | L'OREAL S.A. (FR) | 2004-02-12 | — | — | US | disclosed |
| EP-1333021-A2 | Compositions containing derivatives of jasmonic acid and their use for stimulating skin peeling | L'OREAL (FR) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029839-A1 | Compositions comprising jasmonic acid derivatives and use of these derivatives | CBR1, CBR3, DECR1 | AKR1C4 66/4885AKR1C3 35/4885AKR1C2 91/4885 |
| US-20100179222-A1 | COMPOSITIONS COMPRISING JASMONIC ACID DERIVATIVES AND USE OF THESE DERIVATIVES | CBR1, CBR3, DECR1 | AKR1C4 56/4885AKR1C3 48/4885AKR1C2 122/4885 |
| US-12226509-B2 | Cosmetic composition comprising a pasty fatty substance and a non-ionic derivative of hydrophobic-modified cellulose | NOTUM, FABP4, UGCG | AKR1C4 3657/4885AKR1C3 3518/4885AKR1C2 3525/4885 |
| US-20230065230-A1 | ANTIMICROBIAL MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL)BUTAN-2-ONE AND AN ACID OR SILVER-BASED COMPOUND, AND COSMETIC COMPOSITION CONTAINING SAME | KRT18, CUTA, EBP | AKR1C4 1227/4885AKR1C3 900/4885AKR1C2 892/4885 |
| US-20100168041-A1 | COMBINATION OF MONOSACCHARIDES AND DESQUAMATING AGENTS, AND USE THEREOF | MAN2A1, MANBA, DPM1 | AKR1C4 3183/4885AKR1C3 3017/4885AKR1C2 2970/4885 |
| US-20120157527-A1 | COSMETIC USE OF A JASMONIC ACID DERIVATIVE FOR TREATING THE HAIR AND THE SCALP | KRT18, ACOX3, PDIA3 | AKR1C4 22/4885AKR1C3 6/4885AKR1C2 129/4885 |
| US-12256733-B2 | Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an acid or silver-based compound, and cosmetic composition containing same | KRT18, CUTA, EBP | AKR1C4 1227/4885AKR1C3 900/4885AKR1C2 892/4885 |
| US-20110152150-A1 | CLEANSING COMPOSITION | PHOSPHO1, DEGS1, SGMS1 | AKR1C4 2809/4885AKR1C3 2378/4885AKR1C2 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.