Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059013 | 0.71 | KDM4E (0.39) | BACE1KDM4EHRH3PFKFB3PARP1 | |
| SCHEMBL28048966 | 0.68 | BACE1 (0.38) | BACE1KDM4EHRH3PARP1ADRA2A | |
| SCHEMBL14661207 | 0.65 | KDM4E (0.55) | BACE1KDM4EPFKFB3PARP1DYRK1A | |
| SCHEMBL12700128 | 0.64 | ALDH1A1 (0.56) | BACE1KDM4EPFKFB3PARP1F7 | |
| SCHEMBL11331470 | 0.63 | TDP1 (0.37) | KDM4EPKM | |
| SCHEMBL11058519 | 0.62 | KDM4E (0.51) | BACE1KDM4EPFKFB3PKMMETAP2 | |
| SCHEMBL30369296 | 0.62 | BACE1 (0.46) | BACE1KDM4EPFKFB3PARP1DYRK1A | |
| SCHEMBL22573215 | 0.62 | BACE1 (0.46) | BACE1KDM4EPFKFB3PARP1DYRK1A | |
| SCHEMBL30485659 | 0.62 | BACE1 (0.46) | BACE1KDM4EPFKFB3PARP1DYRK1A | |
| SCHEMBL28215693 | 0.60 | HPGD (0.58) | BACE1KDM4EHRH3ATMMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474774-A | Acridone substituted phosphorus compounds, compositions containing same and insecticidal method of use | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |