Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27995131 | 0.84 | KDM4E (0.40) | CTSDATMKDM4E | |
| SCHEMBL28048968 | 0.80 | ESR1 (0.45) | BACE1KMT2AKDM4E | |
| SCHEMBL11058817 | 0.68 | BACE1 (0.36) | BACE1CYP11B1CYP11B2HRH3CTSD | |
| SCHEMBL12700128 | 0.66 | ALDH1A1 (0.56) | BACE1CTSDPARP1MEN1KMT2A | |
| SCHEMBL25086408 | 0.64 | AADAT (0.51) | PNMTAADATPARP1PARP10 | |
| SCHEMBL11059013 | 0.62 | KDM4E (0.39) | BACE1HRH3CTSDATMPARP1 | |
| SCHEMBL10271356 | 0.62 | KDM4E (0.42) | BACE1CTSDPARP1MEN1KMT2A | |
| SCHEMBL22717988 | 0.61 | BACE1 (0.76) | BACE1KDM4E | |
| SCHEMBL22573215 | 0.61 | BACE1 (0.46) | BACE1PARP1MEN1KMT2AKDM4E | |
| SCHEMBL30369296 | 0.61 | BACE1 (0.46) | BACE1PARP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103477224-B | Blood collection device containing lysophospholipase inhibitor | BECTON, DICKINSON AND CO. (US) | 2015-12-23 | — | — | CN | disclosed |