Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063327 | 0.83 | KDM4E (0.65) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11158624 | 0.76 | MAPT (0.59) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11059968 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL10855351 | 0.75 | KDM4E (0.58) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11057496 | 0.75 | SMN1; SMN2 (1.00) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11162984 | 0.75 | HTT (0.68) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11467433 | 0.73 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11165297 | 0.72 | L3MBTL1 (0.70) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11010979 | 0.71 | SMN1; SMN2 (0.58) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL11062897 | 0.71 | KDM4E (0.74) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444774-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1984-04-24 | — | — | US | disclosed |