Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 6/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057496 | 0.79 | SMN1; SMN2 (1.00) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22342534 | 0.79 | KDM4E (1.00) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10123160 | 0.75 | KDM4E (0.67) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11009952 | 0.75 | CYP2A6 (0.46) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11059625 | 0.71 | ALDH1A1 (0.72) | KDM4EMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15984859 | 0.69 | CYP2A6 (0.62) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL259453 | 0.69 | ALDH1A1 (1.00) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10991094 | 0.69 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL22342511 | 0.69 | KDM4E (0.60) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL3714930 | 0.68 | KDM4E (0.52) | KDM4EMAPTMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444774-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1984-04-24 | — | — | US | disclosed |