Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953334 | 0.78 | CA12 (0.48) | CA12CA1CA2CA4CA7 | |
| SCHEMBL890657 | 0.77 | KEAP1 (0.48) | KEAP1MAOA | |
| SCHEMBL3035516 | 0.73 | MAOA (0.58) | MAOA | |
| SCHEMBL29412508 | 0.72 | KEAP1 (0.53) | CA12CA1CA2CA4CA7 | |
| SCHEMBL24206012 | 0.70 | CA12 (0.42) | CA12CA1CA2CA4CA7 | |
| SCHEMBL1386082 | 0.68 | KEAP1 (0.48) | CA12CA1CA2CA4CA7 | |
| Saccharin SCHEMBL29276959 | 0.67 | CA12 (0.96) | CA12CA1CA2CA4CA7 | |
| SCHEMBL21666737 | 0.67 | MAOA (0.56) | MAOA | |
| SCHEMBL8336188 | 0.66 | CA12 (0.64) | CA12CA1CA2CA4CA7 | |
| SCHEMBL21666868 | 0.65 | MAOA (0.55) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448959-A | Chlorosulfonyl urea triazines | CIBA-GEIGY CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4391976-A | Process for producing arylsulfamates | CIBA-GEIGY CORPORATION (US) | 1983-07-05 | — | — | US | disclosed |