Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778870 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11056793 | 0.86 | HTT (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11056754 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL1159937 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL30252476 | 0.82 | CA1 (0.36) | ALDH1A1CA2ACHEL3MBTL1CYP3A4 | |
| SCHEMBL18828155 | 0.82 | CA1 (0.36) | ALDH1A1CA2ACHEL3MBTL1CYP3A4 | |
| SCHEMBL5196643 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29367415 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL132991 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL470419 | 0.81 | ACHE (0.44) | SMN1; SMN2ALDH1A1CA2ACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444929-A | Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations | THE B. F. GOODRICH COMPANY (US) | 1984-04-24 | — | — | US | claimed |
| US-4444929-A | Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations | THE B. F. GOODRICH COMPANY (US) | 1984-04-24 | — | — | US | disclosed |