Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890031 | 0.87 | MAPT (0.64) | MAPTALDH1A1GAAGPR35SMN1; SMN2 | |
| SCHEMBL11061164 | 0.87 | MAPT (0.64) | MAPTALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL3036107 | 0.87 | MAPT (0.64) | MAPTALDH1A1GAAGPR35SMN1; SMN2 | |
| SCHEMBL10411362 | 0.86 | MAPT (0.56) | MAPTCYP3A4ALDH1A1HPGDKMT2A | |
| SCHEMBL14455041 | 0.84 | MAPT (0.54) | MAPTALDH1A1HPGDKMT2AGAA | |
| SCHEMBL9659046 | 0.84 | KMT2A (0.70) | MAPTCYP3A4ALDH1A1HPGDKMT2A | |
| SCHEMBL9364832 | 0.84 | GPR35 (0.60) | MAPTALDH1A1GAAGPR35SMN1; SMN2 | |
| SCHEMBL11064419 | 0.83 | GAA (0.62) | MAPTCYP3A4KMT2AGAAEPHX1 | |
| SCHEMBL9364621 | 0.83 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDKMT2AGAA | |
| SCHEMBL9365321 | 0.83 | KDR (0.61) | MAPTALDH1A1KMT2AGAAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483707-A | PLANT SAFTENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |