Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137010 | 1.00 | MCHR1 (0.45) | MCHR1KDM4EHPGDPOLBALDH1A1 | |
| SCHEMBL11775839 | 0.86 | SMN1; SMN2 (0.43) | KDM4EHPGDALDH1A1CYP2C19TDP1 | |
| SCHEMBL14286919 | 0.80 | ALDH1A1 (0.46) | KDM4EHPGDALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL19416657 | 0.80 | HTT (0.46) | KDM4EHPGDALDH1A1CYP2C19TDP1 | |
| SCHEMBL11329342 | 0.80 | ALDH1A1 (0.39) | KDM4EHPGDPOLBALDH1A1CYP3A4 | |
| SCHEMBL3683856 | 0.79 | KEAP1 (0.59) | MCHR1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9101224 | 0.79 | KEAP1 (0.59) | MCHR1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9099317 | 0.79 | KEAP1 (0.59) | MCHR1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8778823 | 0.79 | KEAP1 (0.59) | MCHR1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9099940 | 0.79 | KEAP1 (0.59) | MCHR1ALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480021-A | ARYL SULFONE | XEROX CORPORATION (US) | 1984-10-30 | — | — | US | claimed |
| US-4480021-A | ARYL SULFONE | XEROX CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |