Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982887 | 0.81 | AR (0.43) | ARLTA4HTSHRNAAAHTT | |
| SCHEMBL8028948 | 0.80 | AR (0.40) | ARLTA4HTSHRPCSK9NAAA | |
| SCHEMBL9849736 | 0.79 | KCNH2 (0.45) | ARTSHRNAAASMN1; SMN2HTT | |
| SCHEMBL10361208 | 0.79 | KCNH2 (0.45) | ARTSHRNAAASMN1; SMN2HTT | |
| SCHEMBL28646795 | 0.79 | KCNH2 (0.45) | ARTSHRNAAASMN1; SMN2HTT | |
| SCHEMBL11151647 | 0.78 | AR (0.46) | ARTSHRPCSK9NAAAPTGS2 | |
| SCHEMBL1583761 | 0.78 | AR (0.39) | ARLTA4HTSHRPCSK9NAAA | |
| SCHEMBL11358218 | 0.77 | AR (0.45) | ARTSHRPCSK9NAAAPTGS2 | |
| SCHEMBL5077495 | 0.76 | AR (0.37) | ARLTA4HTSHRPCSK9NAAA | |
| SCHEMBL1583764 | 0.76 | AR (0.37) | ARLTA4HTSHRPCSK9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434161-A | ANTICHOLESTEROL | SANDOZ, INC. (US) | 1984-02-28 | — | — | US | disclosed |