Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14954528 | 0.81 | ESR1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL296966 | 0.80 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL8028948 | 0.79 | AR (0.40) | ARTSHRPCSK9LTA4HNAAA | |
| SCHEMBL15302451 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL15302492 | 0.79 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL2293538 | 0.79 | PCSK9 (0.36) | ARTSHRALDH1A1PCSK9NAAA | |
| SCHEMBL24849102 | 0.79 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL8084333 | 0.77 | KCNH2 (0.34) | TSHRALDH1A1LTA4HNAAA | |
| SCHEMBL3982887 | 0.77 | AR (0.43) | ARTSHRALDH1A1LTA4HNAAA | |
| SCHEMBL11060463 | 0.76 | AR (0.40) | ARTSHRPCSK9LTA4HNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907444-A2 | POLYMERIC MICELLES FOR DRUG DELIVERY | Intezyne Technologies Incorporated (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2006107903-A2 | POLYMERIC MICELLES FOR DRUG DELIVERY | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2006-10-12 | — | — | WO | disclosed |