Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583761 | 0.78 | AR (0.39) | ARTSHRPCSK9LTA4HNAAA | |
| SCHEMBL3982887 | 0.77 | AR (0.43) | ARTSHRLTA4HNAAA | |
| SCHEMBL11060463 | 0.76 | AR (0.40) | ARTSHRPCSK9LTA4HNAAA | |
| SCHEMBL8028948 | 0.76 | AR (0.40) | ARTSHRPCSK9LTA4HNAAA | |
| SCHEMBL9849736 | 0.75 | KCNH2 (0.45) | ARTSHRNAAA | |
| SCHEMBL28646795 | 0.75 | KCNH2 (0.45) | ARTSHRNAAA | |
| SCHEMBL10361208 | 0.75 | KCNH2 (0.45) | ARTSHRNAAA | |
| SCHEMBL11151647 | 0.74 | AR (0.46) | ARTSHRPCSK9NAAAPTGS2 | |
| SCHEMBL11358218 | 0.73 | AR (0.45) | ARTSHRPCSK9NAAAPTGS2 | |
| SCHEMBL5077495 | 0.71 | AR (0.37) | ARTSHRPCSK9LTA4HNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488522-A2 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | Hanmi Holdings Co., Ltd. (KR) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046303-A2 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI HOLDINGS CO., LTD. (KR) | 2011-04-21 | — | — | WO | disclosed |