Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054433 | 0.91 | TDP1 (0.66) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL11055494 | 0.85 | MAPT (0.44) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL11123856 | 0.82 | P2RX7 (0.44) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL9653901 | 0.81 | TDP1 (0.46) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL11057290 | 0.81 | ALDH1A1 (0.51) | TDP1ALDH1A1POLBLMNA | |
| Hydrochloric Acid SCHEMBL11057294 | 0.80 | ALDH1A1 (0.50) | TDP1ALDH1A1POLBLMNA | |
| SCHEMBL11063582 | 0.79 | ALDH1A1 (0.48) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL9652192 | 0.79 | MAPT (0.45) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL11055589 | 0.78 | MAPT (0.81) | TDP1MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL11057788 | 0.78 | MAPT (0.65) | TDP1MAPTALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482712-A | FUNGICIDES; HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0010420-B1 | PYRIDYL-SUBSTITUTED THIAZOLIDINE AND 1,3-THIAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AGRICULTURAL COMPOSITIONS CONTAINING SAID DERIVATIVES AND METHODS FOR REGULATING PLANT GROWTH AND PROTECTING PLANTS FROM FUNGI | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |
| US-4436739-A | FUNGICIDES | ELI LILLY AND COMPANY (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0010420-A1 | Pyridyl-substituted thiazolidine and 1,3-thiazine derivatives, processes for their preparation, agricultural compositions containing said derivatives and methods for regulating plant growth and protecting plants from fungi | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |