Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818105 | 0.76 | BCHE (0.42) | BCHEACHECA12CA1CA2 | |
| SCHEMBL2851080 | 0.76 | MGLL (0.56) | NPC1RAB9AKMT2ABCHE | |
| SCHEMBL29025676 | 0.72 | P2RX4 (0.55) | NPC1RAB9AKMT2AGSK3AGSK3B | |
| SCHEMBL31047662 | 0.71 | P2RX4 (0.55) | NPC1RAB9AKMT2AGSK3AGSK3B | |
| SCHEMBL9686147 | 0.71 | P2RX4 (0.55) | NPC1RAB9AKMT2AGSK3AGSK3B | |
| SCHEMBL16280099 | 0.71 | MGLL (0.62) | KMT2ABCHECA12CA1CA2 | |
| SCHEMBL7826151 | 0.70 | NPC1 (0.71) | NPC1RAB9AKMT2AGSK3AGSK3B | |
| SCHEMBL21415451 | 0.69 | MGLL (0.48) | NPC1RAB9AKMT2ABCHECA12 | |
| SCHEMBL1321593 | 0.69 | P2RX4 (0.57) | NPC1RAB9AKMT2AGSK3AGSK3B | |
| SCHEMBL7605340 | 0.68 | MEN1 (0.42) | NPC1RAB9AKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515798-A | INSECTICIDES, OVICIDES, LARVICIDES | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |