Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886574 | 0.93 | ADORA2A (0.49) | ADORA2AADORA2BSMN1; SMN2ANPEPNPEPPS | |
| SCHEMBL10885822 | 0.93 | ADORA2A (0.46) | ADORA2AADORA2BSMN1; SMN2ANPEPNPEPPS | |
| SCHEMBL10896379 | 0.91 | AHCY (0.54) | SMN1; SMN2ANPEPNPEPPSLMNATP53 | |
| SCHEMBL10883897 | 0.88 | ADORA2A (0.48) | ADORA2AADORA2BNPEPPS | |
| SCHEMBL10885276 | 0.88 | ADORA2A (0.52) | ADORA2AADORA2BADORA1NPEPPS | |
| SCHEMBL10887386 | 0.88 | ADORA2A (0.52) | ADORA2AADORA2BADORA1NPEPPS | |
| SCHEMBL10885962 | 0.88 | ADORA2A (0.46) | ADORA2AADORA2BSMN1; SMN2ANPEPNPEPPS | |
| SCHEMBL10884643 | 0.82 | AHCY (0.59) | SMN1; SMN2ANPEPNPEPPSLMNATP53 | |
| SCHEMBL10885229 | 0.82 | ADORA2A (0.52) | ADORA2AADORA2BADORA1 | |
| SCHEMBL11060614 | 0.81 | ADORA2A (0.46) | ADORA2AADORA2BSMN1; SMN2ANPEPNPEPPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |