Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069028 | 0.89 | ALDH1A1 (0.43) | PTGS2ALDH1A1LMNAHPGD | |
| Sulfur Dioxide SCHEMBL11107367 | 0.84 | ALDH1A1 (0.39) | PTGS2ALDH1A1LMNAHPGD | |
| SCHEMBL11059137 | 0.77 | MAPT (0.40) | ALDH1A1LMNAHPGD | |
| SCHEMBL11065593 | 0.74 | PTGS2 (0.38) | PTGS2CES2CES1ALDH1A1LMNA | |
| SCHEMBL11065768 | 0.72 | CNR2 (0.36) | ALDH1A1LMNA | |
| Benzophenone SCHEMBL23014697 | 0.72 | ALDH1A1 (0.67) | CES2CES1NAAAALDH1A1LMNA | |
| SCHEMBL12967454 | 0.70 | KDM4E (0.43) | ALDH1A1LMNAHPGD | |
| Benzophenone SCHEMBL28860378 | 0.70 | ALDH1A1 (0.64) | CES2CES1NAAAALDH1A1LMNA | |
| Tetradecane SCHEMBL27879974 | 0.70 | ALDH1A1 (0.64) | CES2CES1NAAAALDH1A1LMNA | |
| Benzophenone SCHEMBL27879973 | 0.70 | ALDH1A1 (0.64) | CES2CES1NAAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4458081-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1984-07-03 | — | — | US | disclosed |
| US-4454326-A | 5-Aroyl 6-chloro or 6-bromo 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1,1-di-carboxylates | SYNTEX (U.S.A.) INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4347187-A | Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347186-A | Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |