Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884577 | 0.84 | NPC1 (0.48) | LMNAMEN1KMT2ATSHRAAK1 | |
| SCHEMBL10889110 | 0.81 | PKM (0.45) | LMNAMEN1KMT2ATSHRAAK1 | |
| SCHEMBL10140905 | 0.80 | LMNA (0.40) | LMNAMEN1KMT2ATSHRAAK1 | |
| SCHEMBL2268248 | 0.79 | MEN1 (0.55) | LMNAMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL719027 | 0.79 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10887924 | 0.79 | KMT2A (0.52) | LMNAMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8889711 | 0.77 | MEN1 (0.50) | LMNAMEN1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL2099527 | 0.77 | MEN1 (0.52) | LMNAMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3560316 | 0.76 | MEN1 (0.55) | LMNAMEN1KMT2AAAK1SMN1; SMN2 | |
| SCHEMBL6097662 | 0.76 | MEN1 (0.55) | LMNAMEN1KMT2ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |