Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068318 | 0.84 | GABRA1 (0.36) | GABRA1GABRB2CYP3A4TSHRMAPK1 | |
| SCHEMBL30492067 | 0.73 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL11855962 | 0.69 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4TSHRMAPK1 | |
| SCHEMBL57779 | 0.67 | CYP3A4 (0.46) | GABRA1GABRB2CYP3A4TSHRCASP1 | |
| SCHEMBL2835593 | 0.67 | CYP3A4 (0.46) | GABRA1GABRB2CYP3A4TSHRCASP1 | |
| SCHEMBL1989667 | 0.67 | GABRA1 (0.37) | GABRA1GABRB2 | |
| SCHEMBL583613 | 0.67 | GABRA1 (0.42) | GABRA1GABRB2MAPK1TDP1 | |
| SCHEMBL632310 | 0.65 | CYP3A4 (0.56) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL583614 | 0.65 | GABRA1 (0.41) | GABRA1GABRB2MAPK1TDP1 | |
| SCHEMBL136454 | 0.65 | GABRA1 (0.36) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033168-A1 | POLYACTIC ACID/ALGINATE CONTAINING SURGICAL BARRIER | MAST BIOSURGERY AG (CH) | 2013-03-07 | — | — | WO | disclosed |
| US-20130052236-A1 | COMPOSITE POLYLACTIC ACID/ALGINATE SURGICAL BARRIER | MAST BIOSURGERY (CH) | 2013-02-28 | — | — | US | disclosed |
| US-4446300-A | DIELECTRICS, FORMING TRIS/2-HYDROXYETHYL/ISOCYANURATE IN SITU FROM CYANURIC ACID AND ETHYLENE CARBONATE | THE P. D. GEORGE COMPANY (US) | 1984-05-01 | — | — | US | disclosed |