SCHEMBL632310

SCHEMBL632310

O=C=Nc1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
S100B P04271 1/20 0.44
TRPA1 O75762 1/20 0.43
CA12 O43570 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 4/20 0.42
CA1 P00915 3/20 0.42
MEN1 O00255 3/20 0.42
NPC1 O15118 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GMNN O75496 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CA3 P07451 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4916246 0.89 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1S100B
SCHEMBL13873043 0.87 NR1H2 (0.56) CYP3A4TSHRMAPK1TDP1S100B
SCHEMBL4916235 0.87 CYP3A4 (0.45) CYP3A4TSHRMAPK1TDP1S100B
SCHEMBL14261700 0.87 CYP3A4 (0.80) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15430 0.86 CYP3A4 (0.70) CYP3A4TSHRMAPK1TDP1TRPA1
Hydroquinone SCHEMBL8945771 0.85 CA2 (0.61) CYP3A4TSHRTRPA1CA12CA2
SCHEMBL4154543 0.85 CYP3A4 (0.44) CYP3A4TSHRMAPK1TDP1S100B
SCHEMBL28487083 0.84 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1S100B
SCHEMBL13087340 0.84 ESR1 (0.59) CYP3A4TSHRMAPK1TDP1S100B
SCHEMBL13873042 0.84 ESR1 (0.59) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393698-A Manufacturing method of high-weather-resistance soft film for reflective material 浙江龙游道明光学有限公司 2020-07-10 CN claimed
EP-1866357-B1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF SHOWA DENKO KK (JP) 2012-02-22 EP claimed
US-8044235-B2 (Meth) acryloyl group-containing aromatic isocyanate compound and production process thereof SHOWA DENKO K.K. (JP) 2011-10-25 US claimed
CN-101142252-B Aromatic isocyanate compound containing (meth) acryloyl group and method for producing same SHOWA DENKO KK 2011-08-03 CN claimed
US-20090054543-A1 (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof SHOWA DENKO K.K. (JP) 2009-02-26 US claimed
CN-101142252-A Aromatic isocyanate compound containing (meth) acryloyl group and method for producing same SHOWA DENKO KK (JP) 2008-03-12 CN claimed
EP-1866357-A1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF Showa Denko K.K. (JP) 2007-12-19 EP claimed
WO-2006103979-A1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF SHOWA DENKO K.K. (JP) 2006-10-05 WO claimed
US-4430326-A Method of diminishing glucose levels resulting from endogenous glucagon UNIVERSITY PATENTS, INC. (US) 1984-02-07 US claimed
JP-9235341-A None JP disclosed
JP-60136555-A None JP disclosed
CN-120040773-A Double-end aromatic amine comb type polyether toughened epoxy resin and preparation method thereof 义乌市熙蓝饰品有限公司 2025-05-27 CN disclosed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
EP-0097273-A1 Benzyl urea derivatives, process for their preparation and fungicides for agriculture and horticulture NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-01-04 EP disclosed
EP-0094861-A1 Process for the production of polyurethanes by carbonylation of nitrated hydroxy-aromatic derivatives ELF ATOCHEM S.A. (FR) 1983-11-23 EP disclosed
US-3994886-A ANTIBACTERIAL RECHERCHE ET INDUSTRIE THERAPEUTIQUES (R.I.T.) (BE) 1976-11-30 US disclosed
US-3994887-A ANTIBACTERIAL RECHERCHE ET INDUSTRIE THERAPEUTIQUES (R.I.T.) (BE) 1976-11-30 US disclosed
US-3943096-A Use of hydroxyphenylurethanes for stabilising elastomers CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3933470-A Ester of (alkynyloxy)-, (alkenyloxy)-, and (cyanoalkoxy) carbanilic acids and their use as herbicides AMERICAN CYANAMID COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054543-A1 (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof PRMT5, ACR, PRMT1 CYP3A4 491/4885TSHR 3178/4885MAPK1 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.