SCHEMBL11060949

SCHEMBL11060949

CCCCOC(/C=C/C=C/C(OCCCC)OCCCC)OCCCC

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
DNM1 Q05193 1/20 0.35
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
TSHR P16473 2/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.31
ACHE P22303 1/20 0.31
BACE1 P56817 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11060957 1.00 ADRB2 (0.36) ADRB2ADRB1ADRB3DNM1ATM
SCHEMBL5085663 0.83 ADRB2 (0.35) ADRB2ADRB1ADRB3DNM1ATM
SCHEMBL6656306 0.83 ADRB2 (0.35) ADRB2ADRB1ADRB3DNM1ATM
SCHEMBL28239324 0.77 ADRB2 (0.38) ADRB2ADRB1ADRB3DNM1ATM
SCHEMBL6752694 0.75 TSHR (0.40) ADRB2ADRB1ADRB3DNM1ATM
SCHEMBL2215390 0.75 TSHR (0.39) ADRB2ADRB1ADRB3DNM1ATM
SCHEMBL21967086 0.74 ALDH1A1 (0.38) ALDH1A1CNR1CNR2CYP3A4
SCHEMBL21967102 0.74 ALDH1A1 (0.38) ALDH1A1CNR1CNR2CYP3A4
SCHEMBL21967107 0.73 ALDH1A1 (0.37) ALDH1A1CNR1CNR2CYP3A4
SCHEMBL21967105 0.73 ALDH1A1 (0.37) ALDH1A1CNR1CNR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4466805-A 1,1,6,6-TETRAALKOXY HEXA-2,4-DIENES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-08-21 US disclosed