Biphenyl

Biphenyl

SCHEMBL11060972

OCCOCCOCCOCCOCCOCCOCCOCCO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
RECQL P46063 1/20 0.56
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
MAPK1 P28482 2/20 0.50
TSHR P16473 1/20 0.50
GAA P10253 1/20 0.42
KCNH3 Q9ULD8 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
MMP3 P08254 1/20 0.40
BCL2L1 Q07817 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
IDO1 P14902 1/20 0.39
PTK2B Q14289 1/20 0.39
HPGD P15428 1/20 0.39
APP P05067 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28144699 1.00 ALDH1A1 (0.56) ALDH1A1RECQLKMT2AMEN1MAPK1
Biphenyl SCHEMBL8163374 0.97 ALDH1A1 (0.58) ALDH1A1RECQLKMT2AMEN1MAPK1
Biphenyl SCHEMBL3451308 0.89 ALDH1A1 (0.56) ALDH1A1RECQLKMT2AMEN1MAPK1
Triethylene Glycol SCHEMBL21774925 0.89 MMP3 (0.60) ALDH1A1RECQLKMT2AMEN1MMP3
Di(Hydroxyethyl)Ether SCHEMBL21775243 0.87 MMP3 (0.62) ALDH1A1RECQLKMT2AMEN1MAPK1
SCHEMBL21774917 0.86 ALDH1A1 (0.64) ALDH1A1RECQLKMT2AMEN1MAPK1
SCHEMBL10682298 0.86 ALDH1A1 (0.64) ALDH1A1RECQLKMT2AMEN1MAPK1
Triethylene Glycol SCHEMBL18049849 0.84 ALDH1A1 (0.83) ALDH1A1RECQLKMT2AMEN1MAPK1
Triethylene Glycol SCHEMBL22635002 0.84 MEN1 (0.79) ALDH1A1RECQLKMT2AMEN1MAPK1
Tetraethylene Glycol SCHEMBL28155238 0.84 MEN1 (0.79) ALDH1A1RECQLKMT2AMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4486350-A REDUCTION OF SULFOCHLORIDE WITH REDUCING AGENT IN PRESENCE OF HYDRIODIC ACID CASSELLA AKTIENGESELLSCHAFT (DE) 1984-12-04 US disclosed