Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25683723 | 0.98 | RAB9A (0.97) | RAB9ANPC1THRBPANK3ALDH1A1 | |
| SCHEMBL17346760 | 0.86 | RAB9A (0.78) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL1575500 | 0.85 | RAB9A (0.73) | RAB9ANPC1THRBPANK3GRIN2B | |
| SCHEMBL1574587 | 0.85 | RAB9A (0.73) | RAB9ANPC1THRBPANK3GRIN2B | |
| SCHEMBL30986004 | 0.85 | RAB9A (0.74) | RAB9ANPC1THRBPANK3POLB | |
| SCHEMBL25668724 | 0.85 | RAB9A (0.74) | RAB9ANPC1THRBPANK3ALDH1A1 | |
| SCHEMBL11058349 | 0.85 | RAB9A (1.00) | RAB9ANPC1THRBPANK3ALDH1A1 | |
| SCHEMBL1574803 | 0.83 | RAB9A (0.71) | RAB9ANPC1THRBPANK3GRIN2B | |
| SCHEMBL19860010 | 0.83 | RAB9A (0.71) | RAB9ANPC1THRBPANK3POLB | |
| SCHEMBL27851276 | 0.81 | POLB (0.69) | RAB9ANPC1ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435187-A | SUBSTITUTED UREA COMPOUNDS | SHELL OIL COMPANY (US) | 1984-03-06 | — | — | US | claimed |
| US-4435187-A | SUBSTITUTED UREA COMPOUNDS | SHELL OIL COMPANY (US) | 1984-03-06 | — | — | US | disclosed |
| US-4435187-A | SUBSTITUTED UREA COMPOUNDS | SHELL OIL COMPANY (US) | 1984-03-06 | — | — | US | disclosed |