Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063208 | 1.00 | ITGB3 (0.34) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL11064949 | 0.73 | ITGB3 (0.34) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL10814093 | 0.70 | ITGB1 (0.32) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL9861709 | 0.69 | — | — | |
| SCHEMBL8094790 | 0.65 | — | — | |
| SCHEMBL8767797 | 0.65 | ITGB1 (0.38) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL7430653 | 0.65 | — | — | |
| SCHEMBL10782365 | 0.65 | ITGB1 (0.42) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL11176274 | 0.63 | ITGB1 (0.39) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL10949076 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023887-B1 | 3-SUBSTITUTED BICYCLIC AZETIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND INTERMEDIATES AS WELL AS THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | claimed |
| US-4431588-A | PENACILLINS | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | claimed |
| EP-0023887-A2 | 3-Substituted bicyclic azetidinone derivatives, process for their preparation, and intermediates as well as their preparation | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | claimed |
| EP-0023887-B1 | 3-SUBSTITUTED BICYCLIC AZETIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND INTERMEDIATES AS WELL AS THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | disclosed |
| US-4436661-A | INTERMEDIATES FOR PENICILLIN ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4431588-A | PENACILLINS | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0023887-A2 | 3-Substituted bicyclic azetidinone derivatives, process for their preparation, and intermediates as well as their preparation | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |