Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094790 | 1.00 | — | — | |
| SCHEMBL8110089 | 0.75 | ALDH1A1 (0.37) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL10814097 | 0.72 | TSHR (0.46) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL8766854 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9247739 | 0.69 | POLB (0.40) | POLBALDH1A1NPSR1CREBBP | |
| SCHEMBL7716010 | 0.68 | — | — | |
| SCHEMBL8094825 | 0.67 | ALDH1A1 (0.37) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11063208 | 0.65 | ITGB3 (0.34) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11061398 | 0.65 | ITGB3 (0.34) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9184177 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |