Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TK2 | O00142 | 7/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054269 | 0.94 | RNASE1 (0.57) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11205790 | 0.92 | RNASE1 (0.61) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11205795 | 0.92 | RNASE1 (0.61) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL6235590 | 0.92 | TK1 (0.53) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL6926181 | 0.92 | TK1 (0.53) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11200750 | 0.92 | RNASE1 (0.70) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11200741 | 0.92 | RNASE1 (0.70) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11200745 | 0.92 | RNASE1 (0.70) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11198667 | 0.91 | RNASE1 (0.52) | RNASE1CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11203217 | 0.90 | CYP1A2 (0.65) | RNASE1CYP1A2CYP3A4TSHRTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424211-A | VIRICIDES | REGA INSTITUUT VZW (BE) | 1984-01-03 | — | — | US | disclosed |
| EP-0082668-A1 | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections | BEECHAM GROUP PLC (GB) | 1983-06-29 | — | — | EP | disclosed |