Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056573 | 0.81 | MAPT (0.45) | SMN1; SMN2MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL11059137 | 0.74 | MAPT (0.40) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL8051337 | 0.71 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL275400 | 0.70 | HAO1 (0.56) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL11064162 | 0.68 | RAB9A (0.52) | SMN1; SMN2MAPTRAB9AALDH1A1TSHR | |
| Ethyne SCHEMBL8050785 | 0.67 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL13578644 | 0.66 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL2643155 | 0.66 | MAPT (0.57) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL10389933 | 0.65 | SMN1; SMN2 (0.83) | SMN1; SMN2MAPTL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL11060559 | 0.65 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANFKB1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4458081-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1984-07-03 | — | — | US | disclosed |
| US-4454326-A | 5-Aroyl 6-chloro or 6-bromo 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1,1-di-carboxylates | SYNTEX (U.S.A.) INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4347187-A | Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347186-A | Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |