Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335483 | 0.82 | ATAD2 (0.67) | ATAD2LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL436376 | 0.82 | ATAD2 (0.48) | ATAD2LMNATSHRMAPK1POLB | |
| SCHEMBL6811092 | 0.82 | HDAC1 (0.44) | ATAD2LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL6808194 | 0.81 | ATAD2 (0.44) | ATAD2LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL8224822 | 0.78 | POLB (0.59) | POLBCYP1A2 | |
| SCHEMBL18092293 | 0.78 | GRIN1 (0.47) | ATAD2LMNAMAPK1POLB | |
| SCHEMBL31718454 | 0.78 | ADRA2A (0.47) | ATAD2LMNA | |
| SCHEMBL6812177 | 0.78 | HDAC8 (0.47) | ATAD2LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL6811559 | 0.77 | SRD5A1 (0.42) | ATAD2HDAC1HDAC8HDAC6TSHR | |
| SCHEMBL11062154 | 0.75 | POLB (0.68) | HDAC1HDAC8HDAC6POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |