Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408843 | 0.91 | MAPT (0.83) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL11608031 | 0.86 | MAPT (0.75) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL10557875 | 0.86 | MAPT (0.75) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL626949 | 0.84 | MAPT (0.73) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL10987231 | 0.83 | MAPT (0.71) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL11061083 | 0.83 | MAPT (1.00) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL1503906 | 0.83 | ALDH1A1 (0.71) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL9977891 | 0.83 | MAPT (0.71) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL8162593 | 0.83 | MAPT (0.71) | MAPTCYP19A1ALDH1A1HPGDPOLB | |
| SCHEMBL11510257 | 0.83 | MAPT (0.71) | MAPTCYP19A1ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483707-A | PLANT SAFTENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |