Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537146 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL4218139 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL2594400 | 0.97 | — | — | |
| SCHEMBL17743846 | 0.93 | RECQL (0.46) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL2710123 | 0.89 | — | — | |
| SCHEMBL8029318 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL11674706 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL20597518 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL31336402 | 0.86 | RAB9A (0.48) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7033691 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |