Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23053215 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNAGSK3BKMOMAPK1 | |
| SCHEMBL23053352 | 0.86 | MAPT (0.51) | ALDH1A1LMNAMAPK1PKMTSHR | |
| SCHEMBL5217432 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAGSK3BKMOMAPK1 | |
| SCHEMBL5217443 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAGSK3BKMOMAPK1 | |
| SCHEMBL5634622 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAGSK3BMAPK1AKR1C3 | |
| SCHEMBL25062239 | 0.80 | LMNA (0.57) | ALDH1A1LMNAGSK3BKMOMAPK1 | |
| SCHEMBL3158614 | 0.80 | LMNA (0.52) | ALDH1A1LMNAGSK3BMAPK1PKM | |
| SCHEMBL18212293 | 0.80 | LMNA (0.52) | ALDH1A1LMNAGSK3BMAPK1PKM | |
| SCHEMBL13780574 | 0.79 | HIF1A (0.51) | ALDH1A1LMNAGSK3BMAPK1PKM | |
| SCHEMBL10694781 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAGSK3BKMOPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |