Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.52 |
| ▸ | MAOB | P27338 | 11/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062467 | 0.90 | MAOA (0.63) | MAOAMAOBPDE3BPDE3A | |
| SCHEMBL11071191 | 0.89 | MAOA (0.62) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11068004 | 0.87 | MAOA (0.64) | MAOAMAOBPDE3BPDE3A | |
| SCHEMBL11061905 | 0.85 | PDE3B (0.55) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11066048 | 0.84 | PDE3B (0.58) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL24508389 | 0.84 | MAOA (0.53) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11067790 | 0.84 | PDE3B (0.56) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11063117 | 0.83 | PDE3B (0.64) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11067824 | 0.82 | PDE3B (0.53) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11071181 | 0.82 | PDE3B (0.55) | MAOAMAOBPDE3BPDE3AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |