Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.62 |
| ▸ | MAOB | P27338 | 16/20 | 0.62 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062467 | 0.99 | MAOA (0.63) | MAOAMAOBPDE3BPDE3A | |
| SCHEMBL11068004 | 0.96 | MAOA (0.64) | MAOAMAOBPDE3BPDE3A | |
| SCHEMBL11061852 | 0.89 | MAOA (0.52) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11062764 | 0.88 | MAOA (0.69) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11061905 | 0.87 | PDE3B (0.55) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11063117 | 0.86 | PDE3B (0.64) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11067554 | 0.86 | PDE3B (0.73) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11063992 | 0.85 | PDE3B (0.55) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11067824 | 0.84 | PDE3B (0.53) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11068276 | 0.83 | PDE3B (0.57) | MAOAMAOBPDE3BPDE3AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |