Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 13/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062043 | 0.78 | PDE3B (0.46) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL11061133 | 0.77 | PDE3B (0.51) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL11061345 | 0.77 | PDE3B (0.68) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL7307899 | 0.74 | PDE3B (0.53) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL13635989 | 0.72 | PDE3B (0.57) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL13636473 | 0.72 | PDE3B (0.59) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL7326865 | 0.71 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL13636151 | 0.71 | PDE3B (0.64) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL11062559 | 0.70 | PDE3B (0.61) | PDE3BPDE3AKMT2AALDH1A1TSHR | |
| SCHEMBL11063692 | 0.70 | PDE3B (0.61) | PDE3BPDE3AKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |