Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.46 |
| ▸ | PDE2A | O00408 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852404 | 0.81 | CA12 (0.50) | KDM4E | |
| SCHEMBL30086904 | 0.79 | PDE3B (0.59) | PDE3BPDE3AP2RY12PDE2AMCL1 | |
| SCHEMBL15809257 | 0.79 | PDE3B (0.59) | PDE3BPDE3AP2RY12PDE2AMCL1 | |
| SCHEMBL11062040 | 0.78 | PDE3B (0.55) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL7306355 | 0.73 | KCNA5 (0.40) | PDE3BPDE3AP2RY12KDM4E | |
| SCHEMBL7845649 | 0.73 | CA12 (0.44) | KDM4E | |
| SCHEMBL6485891 | 0.71 | KDM4E (0.49) | PDE3BPDE3AP2RY12PDE2APPARG | |
| SCHEMBL20886118 | 0.71 | PTPN7 (0.67) | PDE3BPDE3AP2RY12PDE2APPARG | |
| SCHEMBL30539402 | 0.71 | PTPN7 (0.67) | PDE3BPDE3AP2RY12PDE2APPARG | |
| SCHEMBL11003744 | 0.70 | SHMT2 (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |