Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068252 | 0.97 | DRD2 (0.62) | DRD2SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11065127 | 0.89 | DRD2 (0.71) | DRD2SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11218793 | 0.88 | MAPT (0.60) | DRD2SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11065270 | 0.86 | MAOA (0.65) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL11062029 | 0.85 | MAOA (0.55) | DRD2SMN1; SMN2MAOAMAOBALDH1A1 | |
| SCHEMBL11058875 | 0.85 | MAOA (0.65) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL2025475 | 0.85 | KCNH2 (0.65) | DRD2SMN1; SMN2MAPTNPC1MAOA | |
| SCHEMBL10570478 | 0.84 | DRD2 (0.85) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL10571753 | 0.84 | DRD2 (0.85) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL23097595 | 0.84 | DRD2 (0.81) | DRD2MAOAMAOBDRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |